Crossfire only works on startup.

The only time crossfire will "work" is on first start-up on my computer. i close CF and re-log, it won't start at all. No error code. Any idea why? Doesn't happen on any other game, and support said they can't help....like they ever do.

Also game has been freezing my whole computer like every other game, not sure if my PC or not. Only on crossfire as well.